Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/87953
Title: Serotonin transporter gene polymorphisms and early parent-infant interactions are related to adult male heart rate response to female crying
Authors: Truzzi, Anna
Bornstein, Marc H.
Senese, Vincenzo P.
Shinohara, Kazuyuki
Setoh, Peipei
Esposito, Gianluca
Keywords: Parent-infant Interaction
Serotonin Transporter Gene
Issue Date: 2017
Source: Truzzi, A., Bornstein, M. H., Senese, V. P., Shinohara, K., Setoh, P., & Esposito, G. (2017). Serotonin transporter gene polymorphisms and early parent-infant interactions are related to adult male heart rate response to female crying. Frontiers in Physiology, 8, 111-.
Series/Report no.: Frontiers in Physiology
Abstract: Adults' adaptive interactions with intimate partners enhance well-being. Here we hypothesized that adult males' physiological responses to opposite-sex conspecifics' distress result from an interaction between an environmental factor (early social interaction with caregivers) and a genetic factor (a polymorphism within the promoter region of the serotonin transporter gene, 5-HTTLPR). We assessed heart rate changes in 42 non-married male adults to distress vocalizations (female, infant, and bonobo cries). Males' early interaction with parents was assessed using the Parental Bonding Instrument. Buccal mucosa cell samples were collected to assess their 5-HTTLPR genotype. A significant interaction emerged between early experience and genetic predisposition. Males with a genetic predisposition for higher sensitivity to environmental factors showed atypical physiological responses to adult female cries according to their experienced early maternal parenting. Environmental experiences and genetic characteristics are associated with adult males' physiological responses to socially meaningfully stimuli. Understanding the mechanisms that modulate responses to opposite-sex conspecifics may improve personal well-being and social adaptiveness.
URI: https://hdl.handle.net/10356/87953
http://hdl.handle.net/10220/45552
DOI: http://dx.doi.org/10.3389/fphys.2017.00111
Rights: © 2017 Truzzi, Bornstein, Senese, Shinohara, Setoh and Esposito. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:HSS Journal Articles

Files in This Item:
File Description SizeFormat 
Serotonin Transporter Gene.pdf533.88 kBAdobe PDFThumbnail
View/Open

Google ScholarTM

Check

Altmetric

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.