Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/88806
Title: Super-contrast photoacoustic resonance imaging
Authors: Gao, Fei
Zhang, Ruochong
Feng, Xiaohua
Liu, Siyu
Zheng, Yuanjin
Keywords: DRNTU::Engineering::Electrical and electronic engineering
Photoacoustic Spectroscopy
Modulation
Issue Date: 2018
Source: Gao, F., Zhang, R., Feng, X., Liu, S., & Zheng, Y. (2018). Super-contrast photoacoustic resonance imaging. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 10494, 104943W-. doi:10.1117/12.2292635
Series/Report no.: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Abstract: In this paper, a new imaging modality, named photoacoustic resonance imaging (PARI), is proposed and experimentally demonstrated. Being distinct from conventional single nanosecond laser pulse induced wideband PA signal, the proposed PARI method utilizes multi-burst modulated laser source to induce PA resonant signal with enhanced signal strength and narrower bandwidth. Moreover, imaging contrast could be clearly improved than conventional single-pulse laser based PA imaging by selecting optimum modulation frequency of the laser source, which originates from physical properties of different materials beyond the optical absorption coefficient. Specifically, the imaging steps is as follows: 1: Perform conventional PA imaging by modulating the laser source as a short pulse to identify the location of the target and the background. 2: Shine modulated laser beam on the background and target respectively to characterize their individual resonance frequency by sweeping the modulation frequency of the CW laser source. 3: Select the resonance frequency of the target as the modulation frequency of the laser source, perform imaging and get the first PARI image. Then choose the resonance frequency of the background as the modulation frequency of the laser source, perform imaging and get the second PARI image. 4: subtract the first PARI image from the second PARI image, then we get the contrast-enhanced PARI results over the conventional PA imaging in step 1. Experimental validation on phantoms have been performed to show the merits of the proposed PARI method with much improved image contrast.
URI: https://hdl.handle.net/10356/88806
http://hdl.handle.net/10220/45933
DOI: 10.1117/12.2292635
Rights: © 2018 Society of Photo-optical Instrumentation Engineers (SPIE). This paper was published in Progress in Biomedical Optics and Imaging - Proceedings of SPIE and is made available as an electronic reprint (preprint) with permission of Society of Photo-optical Instrumentation Engineers (SPIE). The published version is available at: [http://dx.doi.org/10.1117/12.2292635]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
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