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https://hdl.handle.net/10356/83579
Title: | Global transcriptomic responses of Escherichia coli K-12 to volatile organic compounds | Authors: | Yung, Pui Yi Grasso, Letizia Lo Mohidin, Abeed Fatima Acerbi, Enzo Hinks, Jamie Seviour, Thomas Marsili, Enrico Lauro, Federico M. |
Keywords: | DRNTU::Engineering::Environmental engineering Volatile Organic Compounds Escherichia Coli K12 |
Issue Date: | 2016 | Source: | Yung, P. Y., Grasso, L. L., Mohidin, A. F., Acerbi, E., Hinks, J., Seviour, T., . . . Lauro, F. M. (2016). Global transcriptomic responses of Escherichia coli K-12 to volatile organic compounds. Scientific Reports, 6,19899-. doi:10.1038/srep19899 | Series/Report no.: | Scientific Reports | Abstract: | Volatile organic compounds (VOCs) are commonly used as solvents in various industrial settings. Many of them present a challenge to receiving environments, due to their toxicity and low bioavailability for degradation. Microorganisms are capable of sensing and responding to their surroundings and this makes them ideal detectors for toxic compounds. This study investigates the global transcriptomic responses of Escherichia coli K-12 to selected VOCs at sub-toxic levels. Cells grown in the presence of VOCs were harvested during exponential growth, followed by whole transcriptome shotgun sequencing (RNAseq). The analysis of the data revealed both shared and unique genetic responses compared to cells without exposure to VOCs. | URI: | https://hdl.handle.net/10356/83579 http://hdl.handle.net/10220/46656 |
DOI: | 10.1038/srep19899 | Schools: | School of Chemical and Biomedical Engineering Asian School of the Environment |
Organisations: | Singapore Centre for Environmental Life Sciences Engineering | Rights: | © 2016 The Authors (Nature Publishing Group). This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | ASE Journal Articles SCBE Journal Articles SCELSE Journal Articles |
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Global transcriptomic responses of Escherichia coli K-12 to volatile organic compounds.pdf | 1.69 MB | Adobe PDF | View/Open |
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