dc.contributor.authorYung, Pui Yi
dc.contributor.authorGrasso, Letizia Lo
dc.contributor.authorMohidin, Abeed Fatima
dc.contributor.authorAcerbi, Enzo
dc.contributor.authorHinks, Jamie
dc.contributor.authorSeviour, Thomas
dc.contributor.authorMarsili, Enrico
dc.contributor.authorLauro, Federico M.
dc.date.accessioned2018-11-16T08:43:22Z
dc.date.available2018-11-16T08:43:22Z
dc.date.issued2016
dc.identifier.citationYung, P. Y., Grasso, L. L., Mohidin, A. F., Acerbi, E., Hinks, J., Seviour, T., . . . Lauro, F. M. (2016). Global transcriptomic responses of Escherichia coli K-12 to volatile organic compounds. Scientific Reports, 6,19899-. doi:10.1038/srep19899en_US
dc.identifier.urihttp://hdl.handle.net/10220/46656
dc.description.abstractVolatile organic compounds (VOCs) are commonly used as solvents in various industrial settings. Many of them present a challenge to receiving environments, due to their toxicity and low bioavailability for degradation. Microorganisms are capable of sensing and responding to their surroundings and this makes them ideal detectors for toxic compounds. This study investigates the global transcriptomic responses of Escherichia coli K-12 to selected VOCs at sub-toxic levels. Cells grown in the presence of VOCs were harvested during exponential growth, followed by whole transcriptome shotgun sequencing (RNAseq). The analysis of the data revealed both shared and unique genetic responses compared to cells without exposure to VOCs.en_US
dc.description.sponsorshipNRF (Natl Research Foundation, S’pore)en_US
dc.description.sponsorshipMOE (Min. of Education, S’pore)en_US
dc.format.extent18 p.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesScientific Reportsen_US
dc.rights© 2016 The Authors (Nature Publishing Group). This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/en_US
dc.subjectVolatile Organic Compoundsen_US
dc.subjectEscherichia Coli K12en_US
dc.subjectDRNTU::Engineering::Environmental engineeringen_US
dc.titleGlobal transcriptomic responses of Escherichia coli K-12 to volatile organic compoundsen_US
dc.typeJournal Article
dc.contributor.researchSingapore Centre for Environmental Life Sciences and Engineeringen_US
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.contributor.schoolAsian School of the Environmenten_US
dc.identifier.doihttp://dx.doi.org/10.1038/srep19899
dc.description.versionPublished versionen_US


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