Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/88923
Title: Optical frequency domain imaging with a rapidly swept laser in the 1300nm bio-imaging window
Authors: Meleppat, Ratheesh Kumar
Murukeshan, Vadakke Matham
Seah, Leong Keey
Keywords: Spectral Interferometry
Swept Source Optical Coherence Tomography
DRNTU::Engineering::Mechanical engineering
Issue Date: 2015
Source: Meleppat, R. K., Murukeshan, V. M., & Seah, L. K. (2015). Optical frequency domain imaging with a rapidly swept laser in the 1300nm bio-imaging window. Proceedings of SPIE - International Conference on Optical and Photonic Engineering (icOPEN2015), 9524, 95242R-. doi:10.1117/12.2190530
Abstract: Optical frequency domain imaging system (OFDI) in the 1300nm biological imaging window is demonstrated by using a high speed frequency swept laser source. The output of the laser with central wave length of 1320nm is continuously tuned over a bandwidth of 100nm with a repetition rate of 16 KHz. The laser source has an instantaneous coherence length of 6mm and delivers an average power of 12mW. Axial resolution ~ 6μm in the biological tissue and peak sensitivity of 110dB are achieved. The experimentally determined values of the imaging parameters such as the axial resolution, sensitivity and depth range are found to be in good agreement with the theoretically estimated values. The developed system is capable of generating the images of size 512x1024 at a rate of 20 frames per second. High resolution and high contrast images of the finger nail and anterior chamber of a pig’s eye acquired using the developed OFDI system are presented, which demonstrate the feasibility of the system for in-vivo biomedical imaging applications.
URI: https://hdl.handle.net/10356/88923
http://hdl.handle.net/10220/47002
DOI: http://dx.doi.org/10.1117/12.2190530
Rights: © 2015 Society of Photo-optical Instrumentation Engineers (SPIE). This paper was published in Proceedings of SPIE - International Conference on Optical and Photonic Engineering (icOPEN2015) and is made available as an electronic reprint (preprint) with permission of Society of Photo-optical Instrumentation Engineers (SPIE). The published version is available at: [http://dx.doi.org/10.1117/12.2190530]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MAE Conference Papers

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