Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/86198
Title: Palladium-catalyzed para-selective alkylation of electron-deficient arenes
Authors: Jiao, Zhiwei
Lim, Li Hui
Hirao, Hajime
Zhou, Steve Jianrong
Keywords: DRNTU::Science::Chemistry
Alkyl Radicals
Alkylation
Issue Date: 2018
Source: Jiao, Z., Lim, L. H., Hirao, H., & Zhou, S. J. (2018). Palladium-catalyzed para-selective alkylation of electron-deficient arenes. Angewandte Chemie International Edition, 57(21), 6294-6298. doi:10.1002/anie.201801967
Series/Report no.: Angewandte Chemie International Edition
Abstract: Intermolecular alkylations of electron‐deficient arenes proceed with good para selectivity. Palladium catalysts were used to generate nucleophilic alkyl radicals from alkyl halides, which then directly add onto the arenes. The arene scope and the site of alkylation are opposite to those of classical Friedel–Crafts alkylations, which prefer electron‐rich systems.
URI: https://hdl.handle.net/10356/86198
http://hdl.handle.net/10220/48297
ISSN: 1433-7851
DOI: 10.1002/anie.201801967
Rights: © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the peer reviewed version of the following article: Jiao, Z., Lim, L. H., Hirao, H., & Zhou, S. J. (2018). Palladium-catalyzed para-selective alkylation of electron-deficient arenes. Angewandte Chemie International Edition, 57(21), 6294-6298, which has been published in final form at http://dx.doi.org/10.1002/anie.201801967. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

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