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|Title:||Cobalt-catalyzed, N–H imine-directed hydroarylation of styrenes||Authors:||Xu, Wengang
|Issue Date:||2018||Source:||Xu, W., & Yoshikai, N. (2018). Cobalt-catalyzed, N–H imine-directed hydroarylation of styrenes. Organic Letters, 20(5), 1392-1395. doi:10.1021/acs.orglett.8b00164||Series/Report no.:||Organic Letters||Abstract:||A cobalt-catalyzed, N–H imine-directed hydroarylation reaction of styrenes is reported. A variety of diaryl and aryl alkyl N–H imines participated in the reaction to afford the corresponding branched adducts in good yield and regioselectivity. Interestingly, unsymmetrical diaryl imines with modest electronic biases reacted regioselectively at one of the aryl rings. Furthermore, the branched selectivity was reversed for substrates bearing a secondary directing group or a bulky pivaloyl N–H imine.||URI:||https://hdl.handle.net/10356/90279
|ISSN:||1523-7060||DOI:||http://dx.doi.org/10.1021/acs.orglett.8b00164||Rights:||© 2018 American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.8b00164||Fulltext Permission:||open||Fulltext Availability:||With Fulltext|
|Appears in Collections:||SPMS Journal Articles|
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