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Title: Cobalt-catalyzed, N–H imine-directed hydroarylation of styrenes
Authors: Xu, Wengang
Yoshikai, Naohiko
Keywords: Styrenes
Issue Date: 2018
Source: Xu, W., & Yoshikai, N. (2018). Cobalt-catalyzed, N–H imine-directed hydroarylation of styrenes. Organic Letters, 20(5), 1392-1395. doi:10.1021/acs.orglett.8b00164
Series/Report no.: Organic Letters
Abstract: A cobalt-catalyzed, N–H imine-directed hydroarylation reaction of styrenes is reported. A variety of diaryl and aryl alkyl N–H imines participated in the reaction to afford the corresponding branched adducts in good yield and regioselectivity. Interestingly, unsymmetrical diaryl imines with modest electronic biases reacted regioselectively at one of the aryl rings. Furthermore, the branched selectivity was reversed for substrates bearing a secondary directing group or a bulky pivaloyl N–H imine.
ISSN: 1523-7060
Rights: © 2018 American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

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