Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/90279
Title: Cobalt-catalyzed, N–H imine-directed hydroarylation of styrenes
Authors: Xu, Wengang
Yoshikai, Naohiko
Keywords: Styrenes
DRNTU::Science::Chemistry
Hydroarylation
Issue Date: 2018
Source: Xu, W., & Yoshikai, N. (2018). Cobalt-catalyzed, N–H imine-directed hydroarylation of styrenes. Organic Letters, 20(5), 1392-1395. doi:10.1021/acs.orglett.8b00164
Series/Report no.: Organic Letters
Abstract: A cobalt-catalyzed, N–H imine-directed hydroarylation reaction of styrenes is reported. A variety of diaryl and aryl alkyl N–H imines participated in the reaction to afford the corresponding branched adducts in good yield and regioselectivity. Interestingly, unsymmetrical diaryl imines with modest electronic biases reacted regioselectively at one of the aryl rings. Furthermore, the branched selectivity was reversed for substrates bearing a secondary directing group or a bulky pivaloyl N–H imine.
URI: https://hdl.handle.net/10356/90279
http://hdl.handle.net/10220/48493
ISSN: 1523-7060
DOI: http://dx.doi.org/10.1021/acs.orglett.8b00164
Rights: © 2018 American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.8b00164
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

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