Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/90265
Title: | Recent progress in the development of near-infrared organic photothermal and photodynamic nanotherapeutics | Authors: | Zhu, Houjuan Cheng, Penghui Chen, Peng Pu, Kanyi |
Keywords: | DRNTU::Engineering::Chemical engineering Photodynamic Therapy Photothermal Therapy |
Issue Date: | 2018 | Source: | Zhu, H., Cheng, P., Chen, P., & Pu, K. (2018). Recent progress in the development of near-infrared organic photothermal and photodynamic nanotherapeutics. Biomaterials Science, 6(4), 746-765. doi:10.1039/C7BM01210A | Series/Report no.: | Biomaterials Science | Abstract: | Phototherapies including photothermal therapy (PTT) and photodynamic therapy (PDT) have gained considerable attention due to their high tumor ablation efficiency, excellent spatial resolution and minimal side effects on normal tissue. In contrast to inorganic nanoparticles, near-infrared (NIR) absorbing organic nanoparticles bypass the issue of metal-ion induced toxicity and thus are generally considered to be more biocompatible. Moreover, with the guidance of different kinds of imaging methods, the efficacy of cancer phototherapy based on organic nanoparticles has shown to be optimizable. In this review, we summarize the synthesis and application of NIR-absorbing organic nanoparticles as phototherapeutic nanoagents for cancer phototherapy. The chemistry, optical properties and therapeutic efficacies of organic nanoparticles are firstly described. Their phototherapy applications are then surveyed in terms of therapeutic modalities, which include PTT, PDT and PTT/PDT combined therapy. Finally, the present challenges and potential of imaging guided PTT/PDT are discussed. | URI: | https://hdl.handle.net/10356/90265 http://hdl.handle.net/10220/48503 |
ISSN: | 2047-4830 | DOI: | 10.1039/C7BM01210A | Schools: | School of Chemical and Biomedical Engineering | Rights: | © 2018 The Author(s). All rights reserved. This paper was published by The Royal Society of Chemistry in Biomaterials Science and is made available with permission of The Author(s). | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | SCBE Journal Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Recent progress in the development of near-infrared organic photothermal and photodynamic nanotherapeutics.pdf | 1.72 MB | Adobe PDF | View/Open |
SCOPUSTM
Citations
1
255
Updated on Mar 15, 2024
Web of ScienceTM
Citations
1
238
Updated on Oct 26, 2023
Page view(s) 50
486
Updated on Mar 18, 2024
Download(s) 5
574
Updated on Mar 18, 2024
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.