Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/91257
Title: Pulsed laser diode based desktop photoacoustic tomography for monitoring wash-in and wash-out of dye in rat cortical vasculature
Authors: Kalva, Sandeep Kumar
Upputuri, Paul Kumar
Rajendran, Praveenbalaji
Dienzo, Rhonnie Austria
Pramanik, Manojit
Keywords: Acoustic Reflector
Bioengineering
DRNTU::Engineering::Chemical engineering
Issue Date: 2019
Source: Kalva, S. K., Upputuri, P. K., Rajendran, P., Dienzo, R. A., & Pramanik, M. (2019). Pulsed laser diode based desktop photoacoustic tomography for monitoring wash-in and wash-out of dye in rat cortical vasculature. Journal of Visualized Experiments, (147). doi:10.3791/59764
Series/Report no.: Journal of Visualized Experiments
Abstract: Photoacoustic (PA) tomography (PAT) imaging is an emerging biomedical imaging modality useful in various preclinical and clinical applications. Custom-made circular ring array-based transducers and conventional bulky Nd:YAG/OPO lasers inhibit translation of the PAT system to clinics. Ultra-compact pulsed laser diodes (PLDs) are currently being used as an alternative source of near-infrared excitation for PA imaging. Highspeed dynamic in vivo imaging has been demonstrated using a compact PLD-based desktop PAT system (PLD-PAT). A visualized experimental protocol using the desktop PLD-PAT system is provided in this work for dynamic in vivo brain imaging. The protocol describes the desktop PLDPAT system configuration, preparation of animal for brain vascular imaging, and procedure for dynamic visualization of indocyanine green (ICG) dye uptake and clearance process in rat cortical vasculature.
URI: https://hdl.handle.net/10356/91257
http://hdl.handle.net/10220/48791
DOI: 10.3791/59764
Rights: © 2019 The Author(s) (Journal of Visualized Experiments). All rights reserved. This paper was published in Journal of Visualized Experiments and is made available with permission of The Author(s) (Journal of Visualized Experiments).
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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