dc.contributor.authorKalva, Sandeep Kumar
dc.contributor.authorUpputuri, Paul Kumar
dc.contributor.authorRajendran, Praveenbalaji
dc.contributor.authorDienzo, Rhonnie Austria
dc.contributor.authorPramanik, Manojit
dc.date.accessioned2019-06-18T03:14:35Z
dc.date.available2019-06-18T03:14:35Z
dc.date.copyright2019
dc.date.issued2019
dc.identifier.citationKalva, S. K., Upputuri, P. K., Rajendran, P., Dienzo, R. A., & Pramanik, M. (2019). Pulsed laser diode based desktop photoacoustic tomography for monitoring wash-in and wash-out of dye in rat cortical vasculature. Journal of Visualized Experiments, (147). doi:10.3791/59764en_US
dc.identifier.urihttp://hdl.handle.net/10220/48791
dc.description.abstractPhotoacoustic (PA) tomography (PAT) imaging is an emerging biomedical imaging modality useful in various preclinical and clinical applications. Custom-made circular ring array-based transducers and conventional bulky Nd:YAG/OPO lasers inhibit translation of the PAT system to clinics. Ultra-compact pulsed laser diodes (PLDs) are currently being used as an alternative source of near-infrared excitation for PA imaging. Highspeed dynamic in vivo imaging has been demonstrated using a compact PLD-based desktop PAT system (PLD-PAT). A visualized experimental protocol using the desktop PLD-PAT system is provided in this work for dynamic in vivo brain imaging. The protocol describes the desktop PLDPAT system configuration, preparation of animal for brain vascular imaging, and procedure for dynamic visualization of indocyanine green (ICG) dye uptake and clearance process in rat cortical vasculature.en_US
dc.description.sponsorshipNMRC (Natl Medical Research Council, S’pore)en_US
dc.format.extent6 p.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesJournal of Visualized Experimentsen_US
dc.rights© 2019 The Author(s) (Journal of Visualized Experiments). All rights reserved. This paper was published in Journal of Visualized Experiments and is made available with permission of The Author(s) (Journal of Visualized Experiments).en_US
dc.subjectBioengineeringen_US
dc.subjectAcoustic Reflectoren_US
dc.subjectDRNTU::Engineering::Chemical engineeringen_US
dc.titlePulsed laser diode based desktop photoacoustic tomography for monitoring wash-in and wash-out of dye in rat cortical vasculatureen_US
dc.typeJournal Article
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.identifier.doihttps://dx.doi.org/10.3791/59764
dc.description.versionPublished versionen_US
dc.identifier.rims214584


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