Please use this identifier to cite or link to this item:
|Title:||International union of basic and clinical pharmacology. C. nomenclature and properties of calcium-activated and sodium-activated potassium channels||Authors:||Kaczmarek, Leonard K.
Aldrich, Richard W.
Chandy, Kanianthara George
Wei, Aguan D.
Na+ and Cl−
|Issue Date:||2017||Source:||Kaczmarek, L. K., Aldrich, R. W., Chandy, K. G., Grissmer, S., Wei, A. D., & Wulff, H. (2016). International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels. Pharmacological Reviews, 69(1), 1-11. doi:10.1124/pr.116.012864||Series/Report no.:||Pharmacological Reviews||Abstract:||A subset of potassium channels is regulated primarily by changes in the cytoplasmic concentration of ions, including calcium, sodium, chloride, and protons. The eight members of this subfamily were originally all designated as calcium-activated channels. More recent studies have clarified the gating mechanisms for these channels and have documented that not all members are sensitive to calcium. This article describes the molecular relationships between these channels and provides an introduction to their functional properties. It also introduces a new nomenclature that differentiates between calcium- and sodium-activated potassium channels.||URI:||https://hdl.handle.net/10356/82498
|ISSN:||0031-6997||DOI:||http://dx.doi.org/10.1124/pr.116.012864||Rights:||© 2016 The American Society for Pharmacology and Experimental Therapeutics. All rights reserved.||Fulltext Permission:||none||Fulltext Availability:||No Fulltext|
|Appears in Collections:||LKCMedicine Journal Articles|
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.