Excluding severe bacterial infection in neutrophilic dermatoses with systemic manifestations : negative predictive value of procalcitonin
Yeo, Pei Ming
Yew, Yik Weng
Tey, Hong Liang
Date of Issue2018
Lee Kong Chian School of Medicine (LKCMedicine)
Extensive neutrophilic activation and infiltration occur in a number of dermatological conditions, resulting in typical features of pyrexia, neutrophilia, and raised erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). These conditions are namely generalised pustular psoriasis, acute generalised exanthematous pustulosis (AGEP) and Sweet syndrome, and they are termed as neutrophilic dermatoses with systemic manifestations. Their presentation is similar to that in patients with severe bacterial infections, such as severe pneumonia, peritonitis, meningitis, pyelonephritis and sepsis.
Annals of the Academy of Medicine, Singapore
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