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Title: Open questions : how to get developmental biology into shape?
Authors: Saunders, Timothy E.
Ingham, Philip William
Keywords: Science::Medicine
3D Modelling
Issue Date: 2019
Source: Saunders, T. E., & Ingham, P. W. (2019). Open questions : how to get developmental biology into shape?. BMC Biology, 17(1), 17-. doi:10.1186/s12915-019-0636-6
Series/Report no.: BMC Biology
Abstract: Recent technical advances have provided unprecedented insights into the selective deployment of the genome in developing organisms, but how such differential gene expression is used to sculpt the complex shapes and sizes of organs remains unclear. Here, we outline major open questions in organogenesis and suggest how a synthesis between developmental biology and physics can help to address them.
DOI: 10.1186/s12915-019-0636-6
Rights: © 2019 The Author(s). This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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