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|Title:||Bioengineering of metal-organic frameworks for nanomedicine||Authors:||Liu, Yuan
|Issue Date:||2019||Source:||Liu, Y., Zhao, Y., & Chen, X. (2019). Bioengineering of Metal-organic Frameworks for Nanomedicine. Theranostics, 9(11), 3122-3133. doi:10.7150/thno.31918||Series/Report no.:||Theranostics||Abstract:||Controlled structure, tunable porosity, and readily chemical functionalizability make metal-organic frameworks (MOFs) a powerful biomedical tool. Nanoscale MOF particles have been increasingly studied as drug carriers, bioimaging agents, and therapeutic agents due to their excellent physiochemical properties. In this review, we start with MOF as a nanocarrier for drug delivery, covering therapeutic MOF agents followed by a comprehensive discussion of surface bioengineering of MOF for improved biostability, biocompatibility, and targeted delivery. Finally, we detail the challenges and prospects of the future of MOF research for biomedical applications.||URI:||https://hdl.handle.net/10356/89741
|DOI:||http://dx.doi.org/10.7150/thno.31918||Rights:||© 2019 Ivyspring International Publisher. This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.||Fulltext Permission:||open||Fulltext Availability:||With Fulltext|
|Appears in Collections:||SPMS Journal Articles|
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