Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/103638
Title: Application of fluid–structure interaction methods to estimate the mechanics of rupture in Asian abdominal aortic aneurysms
Authors: Canchi, Tejas
Saxena, Ashish
Narayanan, Sriram
Pwee, Esley Chin Hock
Ng, Eddie Yin Kwee
Keywords: Fluid–Structure Interaction
Abdominal Aortic Aneurysm
Issue Date: 2018
Source: Canchi, T., Saxena, A., Ng, E. Y. K., Pwee, E. C.H., & Narayanan, S. (2018). Application of fluid–structure interaction methods to estimate the mechanics of rupture in Asian abdominal aortic aneurysms. BioNanoScience, 8(4), 1035-1044. doi:10.1007/s12668-018-0554-z
Series/Report no.: BioNanoScience
Abstract: Abdominal aortic aneurysms (AAAs) occur because of dilation of the infra-renal aorta to more than 150% of its initial diameter. Progression to rupture is aided by several pathophysiological and biomechanical factors. Surgical intervention is recommended when the aneurysm maximum transverse diameter (DAAA) exceeds 55 mm. A system model that incorporates biomechanical parameters will improve prognosis and establish a relationship between AAA geometry and rupture risk. Two Asian patient-specific AAA geometries were obtained from an IRB-approved vascular database. A biomechanical model based on the fluid–structure interaction (FSI) method was developed for a small aneurysm with DAAA of 35 mm and a large aneurysm with a corresponding diameter of 75 mm. The small aneurysm (patient 1) developed a maximum principal stress (PS1) of 3.16e5 Pa and the large aneurysm (patient 2) developed a PS1 of 2.32e5 Pa. Maximum deformation of arterial wall was 0.0020 m and 0.0022 m for patients 1 and 2 respectively. Location of maximum integral wall shear stress (WSS) (fluid) was different from that of PS1. Induced WSS was also higher in patient 1 (18.74 Pa vs 12.88 Pa). An FSI model incorporating the effect of both the structural and fluid domains aids in better understanding of the mechanics of AAA rupture. Patient 1, having a lower DAAA than patient 2, developed a larger PS1 and WSS. It may be concluded that DAAA may not be the sole determinant of AAA rupture risk.
URI: https://hdl.handle.net/10356/103638
http://hdl.handle.net/10220/49494
ISSN: 2191-1630
DOI: http://dx.doi.org/10.1007/s12668-018-0554-z
Rights: © 2018 Springer Science+Business Media, LLC, part of Springer Nature.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MAE Journal Articles

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