Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/102651
Title: Photoacoustic monitoring of tissue temperature at high temporal resolution
Authors: Upputuri, Paul Kumar
Pramanik, Manojit
Keywords: Photoacoustic Imaging
Tissue Temperature
Engineering::Chemical engineering
Issue Date: 2019
Source: Upputuri, P. K., & Pramanik, M. (2019). Photoacoustic monitoring of tissue temperature at high temporal resolution. Proceedings of SPIE - Photons Plus Ultrasound: Imaging and Sensing 2019. doi:10.1117/12.2508284
Abstract: Monitoring of tissue temperature is necessary for guiding energy-based medical treatments. The local temperature information is also important for the safe deposition of light/heat energy into the surrounding healthy tissue. Existing imaging modalities fail to monitor tissue temperature with high accuracy and high resolution. Photoacoustic sensing of temperature was demonstrated using Q-switched Nd:YAG laser. A temperature sensitivity of ~0.15°C was obtained at a temporal resolution of ~2 s. Photoacoustic imaging is a high-speed, high-resolution, deep tissue imaging modality for both preclinical and clinical applications. In this work, we demonstrate photoacoustic sensing of temperature at high temporal resolution order of microseconds using high repetition rate (7000 Hz) near-infrared (~803 nm) pulsed laser diodes. The system will find applications in radiation therapy, photothermal therapy, photodynamic therapy, etc.
URI: https://hdl.handle.net/10356/102651
http://hdl.handle.net/10220/49738
DOI: https://doi.org/10.1117/12.2508284
Rights: © 2019 Society of Photo-optical Instrumentation Engineers (SPIE). All rights reserved. This paper was published in Proceedings of SPIE - Photons Plus Ultrasound: Imaging and Sensing 2019 and is made available with permission of Society of Photo-optical Instrumentation Engineers (SPIE).
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