Pairwise alignment of the DNA sequence using hypercomplex number representation
Shu, Jian Jun
Ouw, Li Shan
Date of Issue2004
School of Mechanical and Aerospace Engineering
A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex number representation of the DNA base-nucleic acid codes and incorporated with the method of dot matrix analysis and various algorithms of sequence alignment. The problem of DNA sequence alignment can be processed in a rather similar way to pairwise alignment of the protein sequence.
Bulletin of mathematical biology
© 2003 Society for Mathematical Biology. This is the author created version of a work that has been peer reviewed and accepted for publication in Bulletin of Mathematical Biology, published by Elsevier on behalf of Society for Mathematical Biology. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1016/j.bulm.2004.01.005].