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Nanoelectronic biosensing of dynamic cellular activities based on nanostructured materials.

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Nanoelectronic biosensing of dynamic cellular activities based on nanostructured materials.

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Title: Nanoelectronic biosensing of dynamic cellular activities based on nanostructured materials.
Author: Huang, Yinxi.; Chen, Peng.
Copyright year: 2010
Abstract: Detecting subtle cellular activities that occur dynamically as regulated temporally and spatially by molecular machinery is of obvious importance in fundamental biology as well as in drug discovery. Additionally, it demands fast and sensitive detection modality. The emerging nanoelectronic biosensors based on nanostructured materials have shown promising potential to resolve the dynamic biological processes of living cells with high sensitivity and high temporal and spatial resolution. Here, the recent advances in the nanoelectronic biosensing of regulated secretion of biomolecules and bioelectrical activities of ion channels using carbon nanotubes and silicon nanowires are briefl y reviewed. The perspectives and key issues of future development are also discussed.
Subject: DRNTU::Engineering::Bioengineering.
Type: Journal Article
Series/ Journal Title: Advanced materials
School: School of Chemical and Biomedical Engineering
Rights: © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

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