Micro- and nanotechnologies for study of cell secretion
Date of Issue2011
School of Chemical and Biomedical Engineering
Cell secretion or exocytosis is a fundamental and ubiquitous cell function in which intracellular vesicles (50-100 nm in diameter) fuse with the plasma membrane and release their content into the extracellular space. Constitutive exocytosis occurs constantly as a housekeeping activity to release proteins, metabolites, etc. Regulated exocytosis, on the other hand, is only triggered by specific stimuli to release signaling molecules. A classic example is Ca2+ triggered neurotransmitter secretion at neuronal synapses.
© 2011 American Chemical Society. This is the author created version of a work that has been peer reviewed and accepted for publication by Analytical Chemistry, American Chemical Society. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [DOI: http://dx.doi.org/10.1021/ac200358b].