Biofunctionalized nanoarrays of inorganic structures prepared by dip-pen nanolithography
Mirkin, Chad A.
Date of Issue2003
School of Materials Science and Engineering
A dip-pen nanolithography based strategy for fabricating and functionalizing Au nanostructures on a semiconductor substrate is reported. The generation of arrays of nanoscale features functionalized with inorganic nanoparticles and proteins (rabbit IgG) is reported. In the case of rabbit IgG, the bioactivity of the array was demonstrated by monitoring its reaction with fluorophore-labelled anti-rabbit IgG. The methodology reported herein points towards ways of making raised optically active and bioactive nanostructures that could prove useful in stamping methodologies or biosensing applications.
© 2003 IOP Publishing Ltd. This is the author created version of a work that has been peer reviewed and accepted for publication by Nanotechnology, IOP Publishing. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1088/0957-4484/14/10/308 ].