Double spiral detection channel for on-chip chemiluminescence detection
Date of Issue
2012School
School of Mechanical and Aerospace Engineering
Version
Accepted version
Abstract
In this paper, we introduced a three-layered microchip that consists of a double spiral channel design for chemiluminescence (CL) detection and a passive micromixer to facilitate the mixing of reagents. The design with two overlapping spiral channels doubled the CL intensity emitted from the reaction as compared to the design with a single spiral channel. The addition of the passive micromixer improved the signal by 1.5 times. Luminol-based chemiluminescence reaction was used for the characterization of the device. This microchip was successfully tested with the determination of L-cysteine and uric acid.
Subject
DRNTU::Engineering::Mechanical engineering
Type
Journal Article
Series/Journal Title
Sensors and actuators B: chemical
Rights
© 2012 Elsevier B.V. This is the author created version of a work that has been peer reviewed and accepted for publication by Sensors and Actuators B: Chemical, Elsevier B.V. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [DOI: http://dx.doi.org/10.1016/j.snb.2012.04.047].
Collections
http://dx.doi.org/10.1016/j.snb.2012.04.047
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