Controlled growth of peptide nanoarrays on Si/SiOx substrates
Boey, Freddy Yin Chiang
Date of Issue2008
School of Materials Science and Engineering
PAMAM dendrimer nanopatterns on Si/ SiOx substrates generated by dip-pen nanolithography are used as anchoring scaffolds for the growth of peptides in situ by ring-opening polymerization of tryptophan-N-carboxyanhydrides. This new method for the fabrication of peptide nanoarrays (see image) on a solid substrate is unique in that the growth of peptide nanostructures is controlled by the reaction time and the concentration of the tryptophan species.
© 2008 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.