Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/99641
Title: Aptamer-based multicolor fluorescent gold nanoprobes for multiplex detection in homogeneous solution
Authors: Fan, Chunhai
Zhang, Juan
Wang, Lihua
Zhang, Hua
Boey, Freddy Yin Chiang
Song, Shiping
Keywords: DRNTU::Engineering::Materials
Issue Date: 2010
Source: Zhang, J., Wang, L., Zhang, H., Boey, F. Y. C., Song, S., & Fan, C. (2010). Aptamer-based multicolor fluorescent gold nanoprobes for multiplex detection in homogeneous solution. Small, 6(2), 201-204.
Series/Report no.: Small
Abstract: The design of a novel multicolor fluorescent gold nanoprobe for homogeneous detection of small-molecule targets is reported, which combines the specific binding abilities of aptamers with the ultrahigh quenching ability of gold nanoparticles (AuNPs). Dye-tagged aptamers and their complementary sequence with thiol labels are co-assembled at the surface of AuNPs. As a proof of concept, it is demonstrated that such a multicolor fluorescent gold nanoprobe can simultaneously detect adenosine, potassium ion, and cocaine with high selectivity. This potentially generic strategy is shown to be promising for rapid screening of small molecular targets.
URI: https://hdl.handle.net/10356/99641
http://hdl.handle.net/10220/8584
ISSN: 1613-6829
DOI: http://dx.doi.org/10.1002/smll.200901012
Rights: © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
metadata.item.grantfulltext: none
metadata.item.fulltext: No Fulltext
Appears in Collections:MSE Journal Articles

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