Please use this identifier to cite or link to this item:
|Title:||Aquaporin engineering, a computational approach||Authors:||Wei, Xin||Keywords:||Aquaporin Z
Molecular dynamics simulation
|Issue Date:||2009||Source:||Wei, X. (2009, March). Aquaporin engineering, a computational approach. Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore.||Abstract:||Aquaporin is a family of membrane proteins devoted to transporting water molecules across biological membranes. This protein family is ubiquitously present in all three kingdoms of life, the Archea, Eubacteria and Eukaryotes. Water permeation rate is orders of magnitude higher in Aquaporin-embedded membrane than normal lipid bilayer. Moreover, some members of the Aquaporin family, such as Aquaporin Z, have excellent solute rejecting ability against small uncharged solutes like urea, glycerol and glucose. The high transport efficiency and high specificity make Aquaporin Z ideal for industrial application like water purification. Engineers have already taken advantage of this to make Aquaporin-incorporated synthetic membranes for water filtration and generation of salinity energy. Despite all the progresses, difficulties still remain in Aquaporin-based technologies, such as in saline and high pressure conditions. This study aims to investigate those problems with a computational approach. [3rd Award]||URI:||https://hdl.handle.net/10356/95480
|Rights:||© 2009 The Author(s).||metadata.item.grantfulltext:||open||metadata.item.fulltext:||With Fulltext|
|Appears in Collections:||URECA Posters|
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.