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Title: An integrated hollow-core photonic crystal fiber transverse optical trapping system for optical manipulation and detection
Authors: Shinoj, V. K.
Murukeshan, Vadakke Matham
Issue Date: 2012
Source: Shinoj, V. K., & Murukeshan, V. M. (2012). An integrated hollow-core photonic crystal fiber transverse optical trapping system for optical manipulation and detection. Journal of Applied Physics, 111(2), 023106-.
Series/Report no.: Journal of Applied Physics
Abstract: Optical manipulation, separation, and detection of biological cells have immense potential biomedical applications, for example, in disease detection. In this paper, we present optical manipulation and detection of micron sized fluorescent particles inside hollow-core photonic crystal fiber (HC-PCF) by transverse optical trapping. An optical trapping system is designed where a near-infrared laser light is focused using a microscope objective to create an optical trap across a liquid-filled HC-PCF. The fluorescent microsphere particles trapped in the core of HC-PCF using the laser induced optical force further undergo imaging and fluorescence spectroscopic analysis. It is illustrated that the proposed method can track the particle into a different medium using the optical trap as well. The obtained results indicate that this proposed method has tangible potential for developing HC-PCF based lab-on-a-chip bio/chemical sensors capable of detecting reagents in ultra low sample volumes.
ISSN: 0021-8979
DOI: 10.1063/1.3676248
Rights: © 2012 American Institute of Physics. This paper was published in Journal of Applied Physics and is made available as an electronic reprint (preprint) with permission of American Institute of Physics. The paper can be found at the following official DOI: []. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law.
Fulltext Permission: open
Fulltext Availability: With Fulltext
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