Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/100629
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dc.contributor.authorGe, Shenguangen
dc.contributor.authorYan, Meien
dc.contributor.authorLu, Juanjuanen
dc.contributor.authorZhang, Mengen
dc.contributor.authorYu, Fengen
dc.contributor.authorYu, Jinghuaen
dc.contributor.authorSong, Xianrangen
dc.contributor.authorYu, Shilinen
dc.date.accessioned2013-07-09T02:54:31Zen
dc.date.accessioned2019-12-06T20:25:38Z-
dc.date.available2013-07-09T02:54:31Zen
dc.date.available2019-12-06T20:25:38Z-
dc.date.copyright2011en
dc.date.issued2011en
dc.identifier.citationGe, S., Yan, M., Lu, J., Zhang, M., Yu, F., Yu, Jinghua, et al. (2011). Electrochemical biosensor based on graphene oxide–Au nanoclusters composites for l-cysteine analysis. Biosensors and Bioelectronics, 31, 49-54.en
dc.identifier.issn0956-5663en
dc.identifier.urihttps://hdl.handle.net/10356/100629-
dc.description.abstractIn this paper, a linker-free connected graphene oxide/Au nanocluster (GO–Au NCs) composite was prepared under sonication through electrostatic interactions, and characterized by transmission electron microscope (TEM), atomic force microscope (AFM), ultraviolet–visible (UV–vis) and FT-IR spectrum. The morphological and structural characterizations evidence that the Au NCs can be efficiently decorated on the GO. The electrochemical investigations indicated that GO–Au NCs composite has an important role in the electrocatalytic activity towards the oxidation of l-cysteine (CySH). The GO–Au NCs composite modified electrode shows a large determination range from 0.05 to 20.0 μmol/L, a remarkably low detection limit is 0.02 μmol/L and low oxidation potential (+0.387). It was found that metal ions, carbohydrates, nucleotide acids and amino acids had no distinct effect on the determination of l-cysteine. In addition, the sensor has some important advantages such as simple preparation, fast response, good stability and high reproducibility. The direct determination of free reduced and total CySH in human urine samples has been successfully carried out without the assistance of any separation techniques.en
dc.language.isoenen
dc.relation.ispartofseriesBiosensors and bioelectronicsen
dc.rights© 2011 Elsevier B.V.en
dc.titleElectrochemical biosensor based on graphene oxide–Au nanoclusters composites for l-cysteine analysisen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Mechanical and Aerospace Engineeringen
dc.identifier.doi10.1016/j.bios.2011.09.038en
item.fulltextNo Fulltext-
item.grantfulltextnone-
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