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https://hdl.handle.net/10356/101016| Title: | The acid free asymmetric intermolecular α-alkylation of aldehydes in fluorinated alcohols | Authors: | Xiao, Jian Zhao, Kai Loh, Teck-Peng |
Issue Date: | 2012 | Source: | Xiao, J., Zhao, K., Loh, T.-P. (2012). The acid free asymmetric intermolecular α-alkylation of aldehydes in fluorinated alcohols. Chemical Communications, 48(29), 3548-3550. | Series/Report no.: | Chemical communications | Abstract: | The acid free asymmetric intermolecular α-alkylation of aldehydes with alcohols has been discovered using trifluoroethanol as solvent. This unprecedented system affords the enantioenriched functionalized primary alcohols (after NaBH4 reduction) in high yields and good to excellent enantioselectivities with wide substrate scope in the absence of any acid additive. | URI: | https://hdl.handle.net/10356/101016 http://hdl.handle.net/10220/11102 |
DOI: | 10.1039/c2cc30261f | Schools: | School of Physical and Mathematical Sciences | Rights: | © 2012 The Royal Society of Chemistry. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
| Appears in Collections: | SPMS Journal Articles |
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