Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/101252
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dc.contributor.authorRice, Scott A.en
dc.contributor.authorKumar, Nareshen
dc.contributor.authorHo, Kitty Ka Kiten
dc.contributor.authorCole, Neridaen
dc.contributor.authorChen, Renxunen
dc.contributor.authorWillcox, Mark D. P.en
dc.date.accessioned2013-07-05T04:39:18Zen
dc.date.accessioned2019-12-06T20:35:40Z-
dc.date.available2013-07-05T04:39:18Zen
dc.date.available2019-12-06T20:35:40Z-
dc.date.copyright2012en
dc.date.issued2012en
dc.identifier.citationHo, K. K. K., Cole, N., Chen, R., Willcox, M. D. P., Rice, S. A., & Kumar, N. (2012). Immobilization of antibacterial dihydropyrrol-2-ones on functional polymer supports to prevent bacterial infections in vivo. Antimicrobial Agents and Chemotherapy, 56(2), 1138-1141.en
dc.identifier.issn0066-4804en
dc.identifier.urihttps://hdl.handle.net/10356/101252-
dc.identifier.urihttp://hdl.handle.net/10220/10995en
dc.description.abstractAntibiotic-resistant Staphylococcus aureus is of great concern, as it causes a wide range of life-threatening infections. The current study demonstrates that dihydropyrrolone (DHP)-coated polyacrylamide substrates are effective in reducing the number of culturable clinical isolates of S. aureus in vitro in a dose-dependent manner and are able to reduce the pathogenic potential of staphylococcal infection in a subcutaneous infection model. Covalently bound DHPs therefore show great potential for use as an antimicrobial strategy in device-related applications.en
dc.language.isoenen
dc.relation.ispartofseriesAntimicrobial agents and chemotherapyen
dc.rights© 2012 American Society for Microbiology.en
dc.titleImmobilization of antibacterial dihydropyrrol-2-ones on functional polymer supports to prevent bacterial infections in vivoen
dc.typeJournal Articleen
dc.identifier.doihttp://dx.doi.org/10.1128/AAC.05814-11en
item.grantfulltextnone-
item.fulltextNo Fulltext-
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