Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/102132
Title: | Distance-mediated plasmonic dimers for reusable colorimetric switches : a measurable peak shift of more than 60 nm | Authors: | Li, Chang Ming Guo, Longhua Ferhan, Abdul Rahim Chen, Hailan Chen, Guonan Hong, Seungpyo Kim, Dong-Hwan |
Keywords: | DRNTU::Engineering::Chemical engineering | Issue Date: | 2013 | Source: | Guo, L., Ferhan, A. R., Chen, H., Li, C. M., Chen, G., Hong, S., et al. (2013). Distance-mediated plasmonic dimers for reusable colorimetric switches : a measurable peak shift of more than 60 nm. Small, 9(2), 234-240. | Series/Report no.: | Small | Abstract: | The first reconfigurable colorimetric DNA switches based on target DNA binding are reported. This DNA binding actuates a change in the interparticle distance between gold nanoparticle dimers. A significant spectral shift of 68 nm is achievable from on-off switching. The reconfigurability is possible owing to thiol and EDC-imidazole coupling which anchors the DNA linkers to the nanoparticles. The huge spectral shift allows the unaided eye to observe single target biomolecular binding event in real time under a darkfield microscope. The limit-of-detection for target molecules in PBS and human serum are 10−13 M and 10−11 M respectively. An improved fabrication strategy via asymmetric functionalization is also described, assisted by solid phase synthesis which minimizes the formation of trimers and multimers. | URI: | https://hdl.handle.net/10356/102132 http://hdl.handle.net/10220/18943 |
ISSN: | 1613-6810 | DOI: | 10.1002/smll.201201061 | Schools: | School of Chemical and Biomedical Engineering | Rights: | © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
Appears in Collections: | SCBE Journal Articles |
SCOPUSTM
Citations
10
60
Updated on Mar 6, 2024
Web of ScienceTM
Citations
5
60
Updated on Oct 30, 2023
Page view(s) 50
557
Updated on Mar 18, 2024
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.