Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/102132
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dc.contributor.authorLi, Chang Mingen
dc.contributor.authorGuo, Longhuaen
dc.contributor.authorFerhan, Abdul Rahimen
dc.contributor.authorChen, Hailanen
dc.contributor.authorChen, Guonanen
dc.contributor.authorHong, Seungpyoen
dc.contributor.authorKim, Dong-Hwanen
dc.date.accessioned2014-03-21T07:16:45Zen
dc.date.accessioned2019-12-06T20:50:08Z-
dc.date.available2014-03-21T07:16:45Zen
dc.date.available2019-12-06T20:50:08Z-
dc.date.copyright2013en
dc.date.issued2013en
dc.identifier.citationGuo, L., Ferhan, A. R., Chen, H., Li, C. M., Chen, G., Hong, S., et al. (2013). Distance-mediated plasmonic dimers for reusable colorimetric switches : a measurable peak shift of more than 60 nm. Small, 9(2), 234-240.en
dc.identifier.issn1613-6810en
dc.identifier.urihttps://hdl.handle.net/10356/102132-
dc.description.abstractThe first reconfigurable colorimetric DNA switches based on target DNA binding are reported. This DNA binding actuates a change in the interparticle distance between gold nanoparticle dimers. A significant spectral shift of 68 nm is achievable from on-off switching. The reconfigurability is possible owing to thiol and EDC-imidazole coupling which anchors the DNA linkers to the nanoparticles. The huge spectral shift allows the unaided eye to observe single target biomolecular binding event in real time under a darkfield microscope. The limit-of-detection for target molecules in PBS and human serum are 10−13 M and 10−11 M respectively. An improved fabrication strategy via asymmetric functionalization is also described, assisted by solid phase synthesis which minimizes the formation of trimers and multimers.en
dc.language.isoenen
dc.relation.ispartofseriesSmallen
dc.rights© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.en
dc.subjectDRNTU::Engineering::Chemical engineeringen
dc.titleDistance-mediated plasmonic dimers for reusable colorimetric switches : a measurable peak shift of more than 60 nmen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.identifier.doi10.1002/smll.201201061en
item.fulltextNo Fulltext-
item.grantfulltextnone-
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