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Title: Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes
Authors: Loo, Joachim Say Chye
Ng, Kee Woei
Zhao, Yun
Howe, Josephine L. C.
Yu, Zhang
Leong, David Tai
Chu, Justin Jang Hann
Keywords: DRNTU::Engineering::Materials::Nanostructured materials
Issue Date: 2013
Source: Zhao, Y., Howe, J. L. C., Yu, Z., Leong, D. T., Chu, J. J. H., Loo, J. S. C., et al. (2013). Exposure to titanium dioxide nanoparticles induces autophagy in primary human keratinocytes. Small, 9(3), 387-392.
Series/Report no.: Small
Abstract: Understanding the mechanisms of cell-nanomaterial interactions is vital in harnessing the potential of using nanomaterials in biomedical applications. By immuno-labeling of LC3 and TEM analysis, it is found that titanium dioxide nanoparticles are internalized by human keratinocytes and induce autophagy. Autophagy appears to play a cytoprotective role in response to toxicity influence exerted by the nanoparticles.
ISSN: 1613-6810
DOI: 10.1002/smll.201201363
Rights: © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:MSE Journal Articles

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