Please use this identifier to cite or link to this item:
Title: Selective Arylation and Vinylation at the α Position of Vinylarenes
Authors: Zou, Yinjun
Qin, Liena
Ren, Xinfeng
Lu, Yunpeng
Li, Yongxin
Zhou, Jianrong Steve
Keywords: DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
Issue Date: 2013
Source: Zou, Y., Qin, L., Ren, X., Lu, Y., Li, Y., & Zhou, J. S. (2013). Selective Arylation and Vinylation at the α Position of Vinylarenes. Chemistry - A European Journal, 19(10), 3504-3511.
Series/Report no.: Chemistry - A European Journal
Abstract: In intermolecular Heck reactions of styrene and vinylarenes, the aryl and vinyl groups routinely insert at the β position. However, selective insertion at the α position has been very rare. Herein, we provide a missing piece in the palette of Heck reaction, which gave >20:1 α selectivity. The key to our success is a new ferrocene 1,1′-bisphosphane (dnpf) that carries 1-naphthyl groups. Our mechanistic studies revealed that the high α selectivity is partly attributable to the steric effect of dnpf. The rigid and bulky 1-naphthyl groups of dnpf sterically disfavor β insertion.
ISSN: 0947-6539
DOI: 10.1002/chem.201203646
Rights: © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

Citations 10

Updated on Jan 16, 2023

Web of ScienceTM
Citations 10

Updated on Jan 30, 2023

Page view(s) 50

Updated on Feb 4, 2023

Google ScholarTM




Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.