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Title: Chiral bicyclic guanidine-catalysed conjugate addition of α-fluoro-β-ketoesters to cyclic enones
Authors: Jing, Zhenzhong
Liu, Jin
Chin, Kek Foo
Chen, Wenchao
Tan, Choon-Hong
Jiang, Zhiyong
Keywords: DRNTU::Science::Chemistry::Organic chemistry
Issue Date: 2014
Source: Jing, Z., Liu, J., Chin, K. F., Chen, W., Tan, C.-H., & Jiang, Z. (2014). Chiral bicyclic guanidine-catalysed conjugate addition of α-fluoro-β-ketoesters to cyclic enones. Australian journal of chemistry, 67(7), 1119-1123.
Series/Report no.: Australian journal of chemistry
Abstract: By utilising a chiral bicyclic guanidine as catalyst and triethylamine as additive, the first asymmetric Michael addition of α-fluoro-β-ketoesters to various cyclic enones has been successfully developed, affording a variety of Michael adducts with potential synthetic utilities with satisfactory stereoselectivity (up to 94 % ee and 4.3 : 1 dr).
ISSN: 0004-9425
DOI: 10.1071/CH14187
Rights: © 2014 CSIRO. This is the author created version of a work that has been peer reviewed and accepted for publication by Australian Journal of Chemistry, CSIRO. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

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