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https://hdl.handle.net/10356/103938
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choo, Joanna A. L. | en |
dc.contributor.author | Thong, Sock Yue | en |
dc.contributor.author | Yap, Jiawei | en |
dc.contributor.author | van Esch, Wim J. E. | en |
dc.contributor.author | Raida, Manfred | en |
dc.contributor.author | Meijers, Rob | en |
dc.contributor.author | Lescar, Julien | en |
dc.contributor.author | Verhelst, Steven H. L. | en |
dc.contributor.author | Grotenbreg, Gijsbert M. | en |
dc.date.accessioned | 2015-01-15T04:26:50Z | en |
dc.date.accessioned | 2019-12-06T21:23:22Z | - |
dc.date.available | 2015-01-15T04:26:50Z | en |
dc.date.available | 2019-12-06T21:23:22Z | - |
dc.date.copyright | 2014 | en |
dc.date.issued | 2014 | en |
dc.identifier.citation | Choo, J. A. L., Thong, S. Y., Yap, J., van Esch, W. J. E., Raida, M., Meijers, R., et al. (2014). Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides. Angewandte chemie international edition, 53(49), 13390-13394. | en |
dc.identifier.issn | 1433-7851 | en |
dc.identifier.uri | https://hdl.handle.net/10356/103938 | - |
dc.description.abstract | Bioorthogonal cleavable linkers are attractive building blocks for compounds that can be manipulated to study biological and cellular processes. Sodium dithionite sensitive azobenzene-containing (Abc) peptides were applied for the temporary stabilization of recombinant MHC complexes, which can then be employed to generate libraries of MHC tetramers after exchange with a novel epitope. This technology represents an important tool for high-throughput studies of disease-specific T cell responses. | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | Angewandte chemie international edition | en |
dc.rights | © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | en |
dc.subject | DRNTU::Science::Biological sciences | en |
dc.title | Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides | en |
dc.type | Journal Article | en |
dc.contributor.school | School of Biological Sciences | en |
dc.identifier.doi | 10.1002/anie.201406295 | en |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
Appears in Collections: | SBS Journal Articles |
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