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https://hdl.handle.net/10356/104154| Title: | Organocatalytic activation of alkylacetic esters as enolate precursors to react with α,β-unsaturated imines | Authors: | Hao, Lin Chen, Shaojin Xu, Jianfeng Tiwari, Bhoopendra Fu, Zhenqian Li, Tong Lim, Jieyan Chi, Robin Yonggui |
Keywords: | DRNTU::Science::Chemistry::Organic chemistry | Issue Date: | 2013 | Source: | Hao, L., Chen, S., Xu, J., Tiwari, B., Fu, Z., Li, T., et al. (2013). Organocatalytic Activation of Alkylacetic Esters as Enolate Precursors to React with α,β-Unsaturated Imines. Organic Letters, 15(19), 4956–4959. | Series/Report no.: | Organic letters | Abstract: | Asymmetric functionalization of alkylacetic esters and their derivatives is traditionally achieved via preformed enolates with chiral auxiliaries. Catalytic versions of such transformations are attractive but challenging. A direct catalytic activation of simple alkylacetic esters via N-heterocyclic carbene organocatalysts to generate chiral enolate intermediates for highly enantioselective reactions is reported. | URI: | https://hdl.handle.net/10356/104154 http://hdl.handle.net/10220/19452 |
DOI: | 10.1021/ol4021805 | Rights: | © 2013 American Chemical Society | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
| Appears in Collections: | SPMS Journal Articles |
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