Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/104160
Title: Direct α-functionalization of simple aldehydes via oxidative N-heterocyclic carbene catalysis
Authors: Mo, Junming
Yang, Ruojie
Chen, Xingkuan
Tiwari, Bhoopendra
Chi, Robin Yonggui
Keywords: DRNTU::Science::Chemistry::Organic chemistry
Issue Date: 2012
Source: Mo, J., Yang, R., Chen, X., Tiwari, B., & Chi, Y. R. (2013). Direct α-Functionalization of Simple Aldehydes via Oxidative N-Heterocyclic Carbene Catalysis. Organic Letters, 15(1), 50–53.
Series/Report no.: Organic letters
Abstract: A direct α-functionalization of simple aldehydes under N-Heterocyclic Carbene (NHC) catalysis and direct generation of ester enolate equivalents from nonfunctionalized aldehydes are disclosed. The catalysis involves selective enolate generation from an oxidatively generated NHC-bounded ester intermediate as a key step. The ester enolate intermediates undergo stereoselective reactions with enones and trifluoromethyl ketones.
URI: https://hdl.handle.net/10356/104160
http://hdl.handle.net/10220/19446
ISSN: 1523-7060
DOI: 10.1021/ol303035r
Rights: © 2012 American Chemical Society.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

SCOPUSTM   
Citations 5

73
Updated on Mar 3, 2021

PublonsTM
Citations 5

73
Updated on Mar 7, 2021

Page view(s) 50

494
Updated on Jul 2, 2022

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.