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|Title:||A synergistic capture strategy for enhanced detection and elimination of bacteria||Authors:||Li, Yong-Qiang
Leow, Wan Ru
|Keywords:||DRNTU::Engineering::Materials::Nanostructured materials||Issue Date:||2014||Source:||Li, Y.-Q., Zhu, B., Li, Y., Leow, W. R., Goh, R., Ma, B., et al. (2014). A Synergistic Capture Strategy for Enhanced Detection and Elimination of Bacteria. Angewandte Chemie International Edition, 53(23), 5837-5841.||Series/Report no.:||Angewandte Chemie international edition||Abstract:||Despite the advanced detection and sterilization techniques available today, the sensitive diagnosis and complete elimination of bacterial infections remain a significant challenge. A strategy is reported for efficient bacterial capture (ca. 90 %) based on the synergistic effect of the nanotopography and surface chemistry of the substrate on bacterial attachment and adhesion. The outstanding bacterial-capture capability of the functionalized nanostructured substrate enables rapid and highly sensitive bacterial detection down to trace concentrations of pathogenic bacteria (10 colony-forming units mL−1). In addition, this synergistic biocapture substrate can be used for efficient bacterial elimination and shows great potential for clinical antibacterial applications.||URI:||https://hdl.handle.net/10356/105188
|ISSN:||1433-7851||DOI:||10.1002/anie.201310135||Rights:||© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.||Fulltext Permission:||none||Fulltext Availability:||No Fulltext|
|Appears in Collections:||MSE Journal Articles|
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