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Title: A synergistic capture strategy for enhanced detection and elimination of bacteria
Authors: Li, Yong-Qiang
Zhu, Bowen
Li, Yuangang
Leow, Wan Ru
Goh, Rubayn
Ma, Bing
Fong, Eileen
Tang, Mark
Chen, Xiaodong
Keywords: DRNTU::Engineering::Materials::Nanostructured materials
Issue Date: 2014
Source: Li, Y.-Q., Zhu, B., Li, Y., Leow, W. R., Goh, R., Ma, B., et al. (2014). A Synergistic Capture Strategy for Enhanced Detection and Elimination of Bacteria. Angewandte Chemie International Edition, 53(23), 5837-5841.
Series/Report no.: Angewandte Chemie international edition
Abstract: Despite the advanced detection and sterilization techniques available today, the sensitive diagnosis and complete elimination of bacterial infections remain a significant challenge. A strategy is reported for efficient bacterial capture (ca. 90 %) based on the synergistic effect of the nanotopography and surface chemistry of the substrate on bacterial attachment and adhesion. The outstanding bacterial-capture capability of the functionalized nanostructured substrate enables rapid and highly sensitive bacterial detection down to trace concentrations of pathogenic bacteria (10 colony-forming units mL−1). In addition, this synergistic biocapture substrate can be used for efficient bacterial elimination and shows great potential for clinical antibacterial applications.
ISSN: 1433-7851
DOI: 10.1002/anie.201310135
Rights: © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:MSE Journal Articles

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