Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/105282
Title: Oxidative N-heterocyclic carbene-catalyzed γ-carbon addition of enals to imines: mechanistic studies and access to antimicrobial compounds
Authors: Chi, Robin Yonggui
Su, Shihu
Jin, Zhichao
Zheng, Peng-Cheng
Cheng, Jiajia
Wang, Yu-Huang
Yang, Song
Jin, Lin-Hong
Song, Bao-An
Keywords: DRNTU::Science::Chemistry::Organic chemistry
Issue Date: 2015
Source: Zheng, P.-C., Cheng, J., Su, S., Jin, Z., Wang, Y.-H., Yang, S., et al. (2015). Oxidative N-heterocyclic carbene-catalyzed γ-carbon addition of enals to imines: mechanistic studies and access to antimicrobial compounds. Chemistry - a European journal, 21(28), 9984-9987.
Series/Report no.: Chemistry - a European journal
Abstract: The reaction mechanism of the γ-carbon addition of enal to imine under oxidative N-heterocyclic carbene catalysis is studied experimentally. The oxidation, γ-carbon deprotonation, and nucleophilic addition of γ-carbon to imine were found to be facile steps. The results of our study also provide highly enantioselective access to tricyclic sulfonyl amides that exhibit interesting antimicrobial activities against X. oryzae, a bacterium that causes bacterial disease in rice growing.
URI: https://hdl.handle.net/10356/105282
http://hdl.handle.net/10220/25965
ISSN: 0947-6539
DOI: 10.1002/chem.201501632
Rights: © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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