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|Title:||Oxidative N-heterocyclic carbene-catalyzed γ-carbon addition of enals to imines: mechanistic studies and access to antimicrobial compounds||Authors:||Chi, Robin Yonggui
|Keywords:||DRNTU::Science::Chemistry::Organic chemistry||Issue Date:||2015||Source:||Zheng, P.-C., Cheng, J., Su, S., Jin, Z., Wang, Y.-H., Yang, S., et al. (2015). Oxidative N-heterocyclic carbene-catalyzed γ-carbon addition of enals to imines: mechanistic studies and access to antimicrobial compounds. Chemistry - a European journal, 21(28), 9984-9987.||Series/Report no.:||Chemistry - a European journal||Abstract:||The reaction mechanism of the γ-carbon addition of enal to imine under oxidative N-heterocyclic carbene catalysis is studied experimentally. The oxidation, γ-carbon deprotonation, and nucleophilic addition of γ-carbon to imine were found to be facile steps. The results of our study also provide highly enantioselective access to tricyclic sulfonyl amides that exhibit interesting antimicrobial activities against X. oryzae, a bacterium that causes bacterial disease in rice growing.||URI:||https://hdl.handle.net/10356/105282
|ISSN:||0947-6539||DOI:||10.1002/chem.201501632||Rights:||© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.||Fulltext Permission:||none||Fulltext Availability:||No Fulltext|
|Appears in Collections:||SPMS Journal Articles|
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