Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/105505
Title: Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells)
Authors: Koh, Tracy
Keywords: Fit2
Min6 cells
Issue Date: 2015
Source: Koh, T. (2015, March). Elucidating the role of fat-inducing transmembrane protein 2 (Fit2) in insulin-producing beta-cells (β-cells). Presented at Discover URECA @ NTU poster exhibition and competition, Nanyang Technological University, Singapore.
Abstract: Fat-Inducing Transmembrane protein 2 (Fit2/Fitm2) is an evolutionarily conserved transmembrane protein. Located on the membrane of the endoplasmic reticulum(ER), Fit2 has been shown to play an important role [1] in the packaging of triglycerides into lipid droplets(LD) within adipocytes (Fig.1). Pancreatic beta-cells (β-cells) secrete insulin. In diabetes β-cell dysfunction is driven partly by lipid stress (lipotoxicity). Fit2 is expressed in β-cells but its function remains elusive. [2nd Award]
URI: https://hdl.handle.net/10356/105505
http://hdl.handle.net/10220/25934
Rights: © 2015 The Author(s).
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:URECA Posters

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