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Title: Postmortem evidence of disseminated Zika virus infection in an adult patient
Authors: Rajahram, Giri Shan
Hale, Gillian
Bhatnagar, Julu
Hiu, Jessie
Thayan, Ravindran
William, Timothy
Wong, Kum Thong
Tambyah, Paul Anantharajah
Yeo, Tsin Wen
Keywords: Viruses
ZIKV Infections
Issue Date: 2019
Source: Rajahram, G. S., Hale, G., Bhatnagar, J., Hiu, J., Thayan, R., William, T., . . . Yeo, T. W. (2019). Postmortem evidence of disseminated Zika virus infection in an adult patient. International Journal of Infectious Diseases, 83, 163-166. doi:10.1016/j.ijid.2019.01.047
Series/Report no.: International Journal of Infectious Diseases
Abstract: Fatal complications associated with the Zika virus (ZIKV) have rarely been reported in adults, and detailed postmortem reports are limited (Musso and Gubler, 2016). ZIKV infection is typically a mild uncomplicated febrile illness associated with arthralgia, rash, and conjunctivitis (Duffy et al., 2009). In adults, fatal and non-fatal neurological complications have been reported, including encephalitis and Guillain–Barré syndrome (Soares et al., 2016, Oehler et al., 2014). Non-neurological fatalities have also been reported sporadically in patients from Latin America, who have presented with an acute febrile illness and multi-organ failure (Sarmiento-Ospina et al., 2016, Zonneveld et al., 2016). This report describes the clinical features and postmortem findings of a 61-year-old Malaysian male with co-morbidities, who had a fatal outcome subsequent to an acute febrile and rash illness, with pre- and postmortem evidence of ZIKV infection.
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2019.01.047
Rights: © 2019 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CCBY-NC-ND license (
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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