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Title: Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community
Authors: Cheng, Yingying
Yam, Joey Kuok Hoong
Cai, Zhao
Ding, Yichen
Zhang, Lian-Hui
Deng, Yinyue
Yang, Liang
Keywords: Biofilms
DRNTU::Science::Biological sciences
Issue Date: 2019
Source: Cheng, Y., Yam, J. K. H., Cai, Z., Ding, Y., Zhang, L.-H., Deng, Y., & Yang, L. (2019). Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community. npj Biofilms and Microbiomes, 5(1), 1-. doi:10.1038/s41522-018-0076-z
Series/Report no.: npj Biofilms and Microbiomes
Abstract: Pseudomonas aeruginosa tends to be among the dominant species in multi-species bacterial consortia in diverse environments. To understand P. aeruginosa’s physiology and interactions with co-existing bacterial species in different conditions, we established physiologically reproducible 18 species communities, and found that P. aeruginosa dominated in mixed-species biofilm communities but not in planktonic communities. P. aeruginosa’s H1 type VI secretion system was highly induced in mixed-species biofilm consortia, compared with its monospecies biofilm, which was further demonstrated to play a key role in P. aeruginosa's enhanced fitness over other bacterial species. In addition, the type IV pili and Psl exopolysaccharide were required for P. aeruginosa to compete with other bacterial species in the biofilm community. Our study showed that the physiology of P. aeruginosa is strongly affected by interspecies interactions, and both biofilm determinants and type VI secretion system contribute to higher P. aeruginosa's fitness over other species in complex biofilm communities.
DOI: 10.1038/s41522-018-0076-z
Rights: © 2019 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/.
Fulltext Permission: open
Fulltext Availability: With Fulltext
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