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dc.contributor.authorXiong, Qiaozhouen
dc.contributor.authorWang, Nanshuoen
dc.contributor.authorLiu, Xinyuen
dc.contributor.authorChen, Sien
dc.contributor.authorLiang, Haitaoen
dc.contributor.authorChen, Shufenen
dc.contributor.authorLiu, Linboen
dc.identifier.citationXiong, Q., Wang, N., Liu, X., Chen, S., Liang, H., Chen, S., & Liu, L. (2019). Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction. Optics Express, 27(5), 6910-6924. doi:10.1364/OE.27.006910en
dc.description.abstractAbstract: In single input state polarization-sensitive optical coherence tomography (PS-OCT) with high resolution, the imperfections of quarter-wave plate (QWP) and the sensitivity roll-off mismatch between the two detection channels cause unpredictable polarization distortion. We present a correction method based on the Jones matrix modeling of the system. In a single input PS-OCT system working at 840 nm with an axial resolution of ~2.3 μm, the method yielded better estimation of retardation and optic axis orientation with significantly reduced noise level, especially in weakly birefringent samples. Numerical simulations and quantitative imaging of a sample of known birefringence were performed to validate the performance. We further demonstrate the advantages of our approach with birefringence imaging of swine retina, rat aortic wall, and rat esophageal mucosa for potential clinical applications.en
dc.description.sponsorshipNRF (Natl Research Foundation, S’pore)en
dc.description.sponsorshipASTAR (Agency for Sci., Tech. and Research, S’pore)en
dc.description.sponsorshipMOE (Min. of Education, S’pore)en
dc.format.extent15 p.en
dc.relation.ispartofseriesOptics Expressen
dc.rights© 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.en
dc.subjectOptic Nerveen
dc.subjectEngineering::Electrical and electronic engineeringen
dc.subjectCircular Polarizationen
dc.titleSingle input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correctionen
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen
dc.contributor.schoolSchool of Electrical and Electronic Engineeringen
dc.description.versionPublished versionen
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