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Title: The effect of intravitreal injections on dry eye, and proposed management strategies
Authors: Laude, Augustinus
Srinagesh, Vishwanath
Tong, Louis
Lim, Jimmy W. K.
Keywords: DRNTU::Science::Medicine
Age-related Macular Degeneration
Issue Date: 2017
Source: Laude, A., Lim, J. W. K., Srinagesh, V., & Tong, L. (2017). The effect of intravitreal injections on dry eye, and proposed management strategies. Clinical Ophthalmology, Volume 11, 1491-1497. doi:10.2147/OPTH.S136500
Series/Report no.: Clinical Ophthalmology
Abstract: Intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents has become a commonly used treatment method for a number of ophthalmic conditions, including age-related macular degeneration. Although anti-VEGF therapy has shown promising results for many patients, there are several aspects of its application that have not been thoroughly investigated. One of these is the development and/or escalation of concurrent dry eye syndrome. Many patients undergoing treatment are already predisposed to dry eye disease due to their age and overall ocular health. As dry eye can have a substantial impact on quality of life, it has become increasingly apparent that the clinical signs and symptoms should be closely monitored and aggressively managed. This will allow for the optimization of patient comfort and visual potential. Here, we discuss the reasons why dry eye may develop during the course of repeated ocular anti-VEGF therapy, highlighting the key concerns about current practices and proposing possible solutions to improve the outcome for the patients.
ISSN: 1177-5467
DOI: 10.2147/OPTH.S136500
Rights: © 2017 Laude et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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