Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/107178
Title: N-heterocyclic carbene organocatalytic reductive β,β-coupling reactions of nitroalkenes via radical intermediates
Authors: Du, Yu
Wang, Yuhuang
Li, Xin
Shao, Yaling
Li, Guohui
Webster, Richard D.
Chi, Robin Yonggui
Keywords: DRNTU::Science::Chemistry::Organic chemistry
Issue Date: 2014
Source: Du, Y., Wang, Y., Li, X., Shao, Y., Li, G., Webster, R. D., et al. (2014). N-heterocyclic carbene organocatalytic reductive β,β-coupling reactions of nitroalkenes via radical intermediates. Organic letters, 16(21), 5678-5681.
Series/Report no.: Organic letters
Abstract: An unprecedented N-heterocyclic carbene catalytic reductive β,β-carbon coupling of α,β-nitroalkenes, by using an organic substrate to mimic the one-electron oxidation role of the pyruvate ferredoxin oxidoreductase (PFOR) in living systems, has been developed. The reaction goes through a radical anion intermediate generated under a catalytic redox process. For the first time, the presence of radical anion intermediate in NHC organocatalysis is observed and clearly verified.
URI: https://hdl.handle.net/10356/107178
http://hdl.handle.net/10220/25333
DOI: 10.1021/ol5027415
Rights: © 2014 American Chemical Society.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SCBE Journal Articles

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