Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/107258
Title: A thioethylalkylamido (TEA) thioester surrogate in the synthesis of a cyclic peptide via a tandem acyl shift
Authors: Taichi, Misako
Hemu, Xinya
Qiu, Yibo
Tam, James P.
Keywords: DRNTU::Science::Biological sciences::Biochemistry
Issue Date: 2013
Source: Taichi, M., Hemu, X., Qiu, Y., & Tam, J. P. (2013). A thioethylalkylamido (TEA) thioester surrogate in the synthesis of a cyclic peptide via a tandem acyl shift. Organic letters, 15(11), 2620-2623.
Series/Report no.: Organic letters
Abstract: The cyclic cystine-knot peptide, kalata B1, was synthesized by employing a novel Fmoc-compatible thioethylalkylamido (TEA) thioester surrogate via an N–S acyl shift followed by a thiol-thioester exchange reaction. TEA thioester surrogate is cost-effective, conveniently prepared in one-step with starting materials, readily available from commercial sources, and highly efficient in preparing peptide thioesters.
URI: https://hdl.handle.net/10356/107258
http://hdl.handle.net/10220/18147
DOI: 10.1021/ol400801k
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SBS Journal Articles

SCOPUSTM   
Citations

48
Updated on Sep 5, 2020

PublonsTM
Citations

45
Updated on Jan 11, 2021

Page view(s)

425
Updated on Jan 18, 2021

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.