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Title: Review of fluorescence suppression techniques in raman spectroscopy
Authors: Wei, Dong
Chen, Shuo
Liu, Quan
Keywords: DRNTU::Science::Medicine::Biomedical engineering
Issue Date: 2015
Source: Wei, D., Chen, S., & Liu, Q. (2015). Review of fluorescence suppression techniques in raman spectroscopy. Applied spectroscopy reviews, 50(5), 387-406.
Series/Report no.: Applied spectroscopy reviews
Abstract: Raman spectroscopy is an important and powerful technique for analyzing the chemical composition of biological or nonbiological samples in many fields. A serious challenge frequently encountered in Raman measurements arises from the existence of the concurrent fluorescence background. The fluorescence intensity is normally several orders of magnitude larger than the Raman scattering signal, especially in biological samples. Such fluorescence background must be suppressed in order to obtain accurate Raman spectra. Several different techniques have been explored for this purpose. These techniques could be generally grouped into time-domain, frequency-domain, wavelength-domain, and computational methods in addition to various Raman enhancement techniques and other unconventional methods. This review briefly describes the fundamental principles of each group of methods, reports the most recent advances, and makes comparison across those major categories of techniques in terms of cost and performance in a hope to guide interested readers to select proper methods for specific applications.
DOI: 10.1080/05704928.2014.999936
Rights: © 2015 Taylor & Francis. This is the author created version of a work that has been peer reviewed and accepted for publication by Applied Spectroscopy Reviews, Taylor & Francis. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [Article DOI:].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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