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Title: Cytotoxicity of layered metal phosphorus chalcogenides (MPXy) nanoflakes; FePS3, CoPS3, NiPS3
Authors: Latiff, Naziah M.
Mayorga-Martinez, Carmen C.
Khezri, Bahareh
Szokolova, Katerina
Sofer, Zdeněk
Fisher, Adrian C.
Pumera, Martin
Keywords: Science::Chemistry
Issue Date: 2018
Source: Latiff, N. M., Mayorga-Martinez, C. C., Khezri, B., Szokolova, K., Sofer, Z., Fisher, A. C., & Pumera, M. (2018). Cytotoxicity of layered metal phosphorus chalcogenides (MPXy) nanoflakes; FePS3, CoPS3, NiPS3. FlatChem, 12, 1-9. doi:10.1016/j.flatc.2018.11.003
Journal: FlatChem
Abstract: Metal phosphorus chalcogenides is a new class of 2D materials that have shown interesting semiconducting, electronic, anisotropic, magnetic, dielectric, structural and optical properties. Recently, NiPS3, FePS3 and CoPS3 in particular have been highlighted for promising potential in important energy applications such as electrocatalysts for water splitting and hydrogen storage. However, little is known about the toxicological hazards that they may pose on humans. Here, we investigated the cytotoxicity of NiPS3, FePS3 and CoPS3 on human lung carcinoma cells (A549) and normal human bronchial cells (BEAS-2B) to address this concern. Upon treatment of these cells with different MPXY materials, we determined the remaining cell viability using water soluble tetrazolium salt (WST-8) assay. We found that CoPS3 was most toxic followed by FePS3 with intermediate toxicity while NiPS3 showed the lowest toxicity among the three materials tested for both cell lines. When viewed with other layered materials, these MPXY samples present comparable toxicities with transition metal dichalcogenides and black phosphorus at low concentrations.
ISSN: 2452-2627
DOI: 10.1016/j.flatc.2018.11.003
Rights: © 2018 Elsevier B. V. All rights reserved. This paper was published in FlatChem and is made available with permission of Elsevier B. V.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

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