Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/137157
Title: Development of optical nanoprobes for molecular imaging of reactive oxygen and nitrogen species
Authors: Zhen, Xu
Pu, Kanyi
Keywords: Engineering::Chemical engineering
Issue Date: 2018
Source: Zhen, X., & Pu, K. (2018). Development of optical nanoprobes for molecular imaging of reactive oxygen and nitrogen species. Nano Research, 11(10), 5258-5280. doi:10.1007/s12274-018-2135-4
Journal: Nano Research
Abstract: Reactive oxygen and nitrogen species (RONS) play important roles in cell signal transduction. However, overproduction of RONS is associated with a series of pathological processes and may disrupt cellular homeostasis, causing oxidative and nitrosative stress. Accurate methods to selectively and specifically monitor RONS in living systems are required to further elucidate the biological functions of these species. Optical imaging possesses high sensitivity, high spatiotemporal resolution, and real-time imaging capability. These qualities are advantageous for the detection of RONS in living systems. This review summarizes the development of optical nanoprobes with near-infrared (NIR) fluorescent, upconversion luminescent, chemiluminescent, or photoacoustic signals for molecular imaging of RONS in living systems. In this review, we discuss the design principles and advantages of RONS-responsive activatable nanoprobes, as well as applications of these optical imaging modalities in different disease models.
URI: https://hdl.handle.net/10356/137157
ISSN: 1998-0124
DOI: 10.1007/s12274-018-2135-4
Rights: © 2018 Tsinghua University Press and Springer-Verlag GmbH Germany, part of Springer Nature. All rights reserved. This paper was published in Nano Research and is made available with permission of Tsinghua University Press and Springer-Verlag GmbH Germany, part of Springer Nature.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

SCOPUSTM   
Citations 10

18
Updated on Mar 10, 2021

PublonsTM
Citations 10

16
Updated on Mar 4, 2021

Page view(s)

92
Updated on Sep 17, 2021

Download(s) 50

35
Updated on Sep 17, 2021

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.