Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/137172
Title: Molecular fluorescence and photoacoustic imaging in the second near-infrared optical window using organic contrast agents
Authors: Jiang, Yuyan
Pu, Kanyi
Keywords: Engineering::Chemical engineering
Issue Date: 2018
Source: Jiang, Y., & Pu, K. (2018). Molecular fluorescence and photoacoustic imaging in the second near-infrared optical window using organic contrast agents. Advanced Biosystems, 2(5), 1700262-. doi:10.1002/adbi.201700262
Journal: Advanced Biosystems
Abstract: Noninvasive near-infrared (NIR) light ranging from 650 to 1000 nm (NIR-I) is widely employed in fundamental research and clinical applications; however, a recently discovered second NIR (NIR-II) window from 1000 to 1700 nm exhibits even better deep-tissue imaging capability due to reduced photon scattering, minimized tissue autofluorescence, and increased applicable power at longer wavelengths. This review focuses on recent advances of organic contrast agents developed for in vivo fluorescence and photoacoustic imaging in the NIR-II optical window. The superiority of the NIR-II over the NIR-I window for molecular imaging is first discussed in detail, followed by discussion of fluorescence and photoacoustic imaging of cancer, vasculature, and the brain using organic contrast agents in the NIR-II window. At last, challenges and perspectives of organic contrast agents for NIR-II in vivo imaging are suggested.
URI: https://hdl.handle.net/10356/137172
ISSN: 2366-7478
DOI: 10.1002/adbi.201700262
Rights: This is the peer reviewed version of the following article: Jiang, Y., & Pu, K. (2018). Molecular fluorescence and photoacoustic imaging in the second near-infrared optical window using organic contrast agents. Advanced Biosystems, 2(5), 1700262-., which has been published in final form at https://doi.org/10.1002/adbi.201700262. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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