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dc.contributor.authorWang, Yan Ruen_US
dc.contributor.authorTou, Zhi Qiangen_US
dc.contributor.authorRavikumar, Raghunandhanen_US
dc.contributor.authorLim, Yi Yinen_US
dc.contributor.authorDing, Zhe Wenen_US
dc.contributor.authorZhao, Chun Liuen_US
dc.contributor.authorSo, Ping Lamen_US
dc.contributor.authorChan, Chi Chiuen_US
dc.identifier.citationWang, Y. R., Tou, Z. Q., Ravikumar, R., Lim, Y. Y., Ding, Z. W., Zhao, C. L., . . ., Chan, C. C. (2019). Reflection-based thin-core modal interferometry optical fiber functionalized with PAA-PBA/PVA for glucose detection under physiological pH. Journal of Lightwave Technology, 37(11), 2773-2777. doi:10.1109/JLT.2018.2879318en_US
dc.description.abstractA phenylboronic-acid-derivatized poly (acrylic acid) (PAA-PBA)/poly(vinyl alcohol) (PVA) functionalized thin-core fiber (TCF) optical sensor is proposed for glucose detection. The unique Michelson-type fiber interferometer sensor was fabricated by splicing a short segment of TCF with a single-mode fiber, where the tip of TCF was melted into a rounded shape. PAA-PBA was synthesized by grafting PBA onto the PAA chain using N-hydroxysuccinimide and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride as coupling reagent. Multilayer films of PAA-PBA and PVA were subsequently functionalized onto the fiber-optic Michelson interferometer structure through layer-by-layer assembly. Experiments showed that the PAA-PBA/PVA functionalized fiber-optic probe exhibits glucose-sensitive behavior under physiological pH. The proposed sensor offers benefits such as simple fabrication, compact size, and glucose selectivity and has potential applications, such as insulin release system, in a biodevice.en_US
dc.relation.ispartofJournal of Lightwave Technologyen_US
dc.rights© 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. The published version is available at:
dc.subjectEngineering::Chemical engineeringen_US
dc.titleReflection-based thin-core modal interferometry optical fiber functionalized with PAA-PBA/PVA for glucose detection under physiological pHen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.contributor.schoolSchool of Electrical and Electronic Engineeringen_US
dc.description.versionAccepted versionen_US
dc.subject.keywordsBiological Sensing and Sensorsen_US
dc.subject.keywordsFiber Opticsen_US
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