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Title: Reflection-based thin-core modal interferometry optical fiber functionalized with PAA-PBA/PVA for glucose detection under physiological pH
Authors: Wang, Yan Ru
Tou, Zhi Qiang
Ravikumar, Raghunandhan
Lim, Yi Yin
Ding, Zhe Wen
Zhao, Chun Liu
So, Ping Lam
Chan, Chi Chiu
Keywords: Engineering::Chemical engineering
Issue Date: 2019
Source: Wang, Y. R., Tou, Z. Q., Ravikumar, R., Lim, Y. Y., Ding, Z. W., Zhao, C. L., . . ., Chan, C. C. (2019). Reflection-based thin-core modal interferometry optical fiber functionalized with PAA-PBA/PVA for glucose detection under physiological pH. Journal of Lightwave Technology, 37(11), 2773-2777. doi:10.1109/JLT.2018.2879318
Journal: Journal of Lightwave Technology 
Abstract: A phenylboronic-acid-derivatized poly (acrylic acid) (PAA-PBA)/poly(vinyl alcohol) (PVA) functionalized thin-core fiber (TCF) optical sensor is proposed for glucose detection. The unique Michelson-type fiber interferometer sensor was fabricated by splicing a short segment of TCF with a single-mode fiber, where the tip of TCF was melted into a rounded shape. PAA-PBA was synthesized by grafting PBA onto the PAA chain using N-hydroxysuccinimide and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride as coupling reagent. Multilayer films of PAA-PBA and PVA were subsequently functionalized onto the fiber-optic Michelson interferometer structure through layer-by-layer assembly. Experiments showed that the PAA-PBA/PVA functionalized fiber-optic probe exhibits glucose-sensitive behavior under physiological pH. The proposed sensor offers benefits such as simple fabrication, compact size, and glucose selectivity and has potential applications, such as insulin release system, in a biodevice.
ISSN: 0733-8724
DOI: 10.1109/JLT.2018.2879318
Schools: School of Chemical and Biomedical Engineering 
School of Electrical and Electronic Engineering 
Rights: © 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. The published version is available at:
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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